I am currently working on B-cell immunology in the lab of Dr. James Thomas. We are interested specifically in tolerance issues and are working with Non-Obese Diabetic mice, which are models of human Type I Diabetes. We also have transgenics which express anti-insulin antibodies. Although Type I Diabetes is a T-cell-mediated disease, recent work has shown that B-cells are needed in this model to initiate disease. It is not known how this works, however.
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[Access to details restricted. Please contact Dr. Kendall for access code. For more information, see Dr. Thomas' webpage (above).] |
All of these projects have been underway for 6 months or less, and are not yet at the abstract stage, though there are some promising early results.
Contact Peggy.KendallATVanderbilt.Edu